Our scientific studies

Dimpless® efficacy on cellulite and fat metabolism disorders has been demonstrated in two gold-standard clinical trials conducted on healthy women between the ages of 25 and 50 years.

Results showed that through targeted action on subcutaneous fat deposits, Dimpless® is not only able to improve skin appearance and reduce cellulite, but it also accelerates a loss of centimeters.

2 clinical studies
76 women
40 mg
1 to 3 months


1_Dimpless_visibly reduces cellulite_EN (1)

Dimpless® visibly reduces cellulite

The visual scoring of cellulite using a validated scale highlighted a significant 10% decrease in cellulite after only 1 month of supplementation.
2_Dimpless_decreases skin folds_EN (1)

Dimpless® decreases skin folds

Several skin folds were measured in areas specifically concerned by subcutaneous fat storage and cellulite i.e. the buttocks (gluteal fold) and the thighs (femoral fold).

Results revealed a decrease in the gluteal and femoral folds compared to the placebo, with a decrease of 23% and 28%, respectively, after 3 months of supplementation.

3_Dimpless_accelerates a reduction in hip and waist size_EN

Dimpless® accelerates a reduction in hip and waist size

Additional measures were assessed in 2 locations specifically concerned with subcutaneous fat storage, but not cellulite, namely the waist and the hips.

Results demonstrated a decrease in hip and waist size, with a decrease of 40% and 46%, respectively, after 3 months of supplementation.

Despite similar weight loss observed in both the Dimpless® and placebo groups, the results were only observed in the Dimpless® group, supporting its action not only on visible cellulite, but more generally on subcutaneous fat deposits, thus accelerating a loss of centimeters.

Dimpless® efficacy on subcutaneous fat deposits and visible cellulite relies on its
multi-parametric effect on fat metabolism.

Mecanisme action_EN

Adipocytes size reduction and collagen fibrosis resorption

While metabolic disorders may induce adipocyte hypertrophy and fibrosis of collagen fibers, Dimpless® has been shown to significantly improve adipose tissue morphology.

After supplementation, both the, cell area and fibrosis decreased by over 50% compared to control.

2_Antioxidant capacity and lipolysis activation_EN

Antioxidant capacity and lipolysis activation

Fat storage is known to alter the oxidative state. 

The expansion of adipose tissue is associated with both an induction of free radicals through the activation of NADPH oxidase and a decrease in endogenous antioxidant enzymes.

Dimpless® supplementation has been shown to normalize the expression of SOD, Catalase, and Glutathione Peroxidase, and also restore lipolysis to a healthy level.

These results were observed in
gold-standard clinical trials.

Lemaire & al, Phytothérapie 2015

Clinical trial of a natural and bioactive melon SuperOxide Dismutase
(SOD B Dimpless®) on cellulite.
Randomized, double-blind, placebo-controlled
41 women/31 – 50 years old/
40mg (480 UI SOD)/2 months

Unpublished, 2019

Randomized, double-blind, placebo-controlled
35 overweight women (25<IMC<31)/25-50 ans/40mg (480 UI SOD)/3 months