From a physiological point of view, cellulite refers to a protrusion of subcutaneous fat into the dermis, characterized by a visible modification of the skin topography1.
Cellulite is known to be linked to two main phenomena, both of which are closely related to a state of oxidative stress:
-Fat accumulation in adipose tissue conductive to adipocyte hypertrophy.
–Conjunctive tissue fibrosis
In some regions of the body, such as women’s hips and thighs, the specific morphology of fatty tissue promotes lipid storage, leading to tension forces within the fat lobules and oxidative stress.
This accumulation of fats and free radicals results in the destruction of collagen fibers and the development of fibrosis, which both limit the evagination of the fat lobules. The skin compartment bulges, leading to the noticeable “orange-peel” aspect of the skin1,4,5.